Magnetic Resonance Spectroscopy (MRS) provides a ‘virtual biopsy’ by measuring the concentrations of chemicals in the brain. MRS is safe, non-invasive, radiation-free, and can be performed on any standard MRI scanner by adding 5 to 15 minutes of scan time to a routine MRI exam. It goes beyond traditional imaging techniques to observe tissue metabolism, measuring biochemicals at concentrations 10,000 times lower than conventional MRI. To date there are over 28,000 academic publications that detail the use of MRS for a wide range of clinician diagnoses including Alzheimer’s Disease, epilepsy, traumatic brain injury, multiple sclerosis, schizophrenia, and metabolic disorders.

Our revolutionary new software package combines the latest processing technology with an intuitive and accessible interface to put all the power of MR spectroscopy in the hands of doctors everywhere.

Cutting Edge Processing

Because we process all your data in the cloud, you always get the most up-to-date algorithms.

Available anywhere

Our browser based viewer means you can access your data from anywhere, any time, on any device.


Automatic reporting

Our context sensitive reports give you the most important information, automatically.

BrainSpec Technology

BrainSpec is a comprehensive web-based software platform designed to make MRS technology accessible to clinicians and researchers alike. The software combines a linear combinations model based post-processing back-end that represents the most accurate method of measuring brain metabolites with a highly intuitive and user-friendly front-end web-based user interface. This combination allows for high analytical performance while maintaining ease of use and results in reduced case processing time, leading to higher output and lower costs.

DICOM, RDA, TWIX, SDAT, G-file. MR spectroscopy data comes in plenty of different formats, and not every processing package will read every file. At BrainSpec we are working with the scanner manufacturers to ensure that no matter where your data comes from, you will be able to process it with us.

State of the art quantification not only gives a concentration estimate for all the metabolites, but also calculates the associated error, so you know just how reliable that number is. What’s more, we automatically color code the concentration table so you can see at a glance which values you can trust.

Our cloud based system means that you can view the results anywhere – from your office, a patient’s bedside or the conference room, and on any device – PC, tablet or smartphone. Our server will interface directly with your hospital PACS to pull in all the other images acquired with the MRS, then when you are done with the analysis you can push your screenshots and reports right back again.

Each scanning protocol comes with a complete set of automatic reports generated for each examined case, to bring all the most important information from the exam together in one easy to reference place. Want to know which voxel has the highest concentration of choline, or how many voxels have significantly depleted NAA? It’s all in the report.

Our Story

The team was formed in May 2015 at a brainstorming session hosted by the iHub at Brigham and Women’s Hospital designed to help clinicians and researchers bring their ideas into reality. Additional collaborators include experienced radiologists, oncologists, neurologists and neurosurgeons at Brigham and Women’s Hospital and Massachusetts General Hospital. Our goal is to put the power of MR Spectroscopy into the hands of clinicians and researchers nationwide, making the virtual biopsy a reality.